How does DNA recombination work? It occurs frequently in many different cell types, and it has important implications for genomic integrity, evolution, and human disease. In the alternate pathway ...

DNA is a mosaic of genetic fragments passed down through generations, but its clarity diminishes over time. While modern testing can trace ancestry through shared markers, the depth of this insight ...

Aberrant segregation was first clearly noted in the 1950s in genetic studies of certain fungi that allow direct examination of their four haploid products of meiosis. Normally in these fungi, a ...

While this shuffling, known as recombination, is essential for genetic diversity, errors in the process can lead to serious reproductive issues. These failures can result in genetic errors that ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Bjarni V. Halldorsson and Kari Stefansson, scientists at deCODE genetics, discuss the paper: Complete recombination map of the human-genome, published in Nature today. The paper continues 25 years of ...

Recombination between 2 different chromosomes has the potential to alter the genetic information in a cell. For example, when homologs recombine, loss of heterozygosity (LOH) can result, in which ...

is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. The techniques involve ...

Herrmann, J.A., A. Koprowska, T.J. Winters, N. Villanueva, V.D. Nikityuk, F. Pek, E.M. Reis, C.Z. Dominguez, D. Davis, E. McPherson, S.R. Rocco, C. Recendez, S.M ...