Candidate VY1706 demonstrates significant reductions of tau at low doses in NHP study; IND and CTA filings anticipated in ...

Reduced Weight Regain: CCT-217 shows promise in preventing weight regain commonly observed after discontinuing incretin ...

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it is scheduled to participate in the following upcoming events: ...

Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are ...

A critical component in this process is the formation of R-loops—open DNA structures where RNA binds, signaling the system to initiate gene silencing. "The 'R' in R-loop stands for RNA.

Gene silencing describes the epigenetic regulation of a gene, at the level of transcription or translation, to prevent gene expression. Mechanisms include DNA methylation, histone modification and ...

This promiscuous binding activity means that miRNA can act on many different mRNAs, potentially silencing hundreds of genes simultaneously. In contrast, when RNAi is guided by siRNA, the entire ...

Oxford-based SynaptixBio, which is developing an antisense oligonucleotide (ASO) to ‘silence’ the expression of a single mutated gene, says the ASO market is set to grow dramatically, largely because ...

Arrowhead Pharmaceuticals (ARWR) has secured a new partnership with Sarepta Therapeutics (SRPT). Under the terms of the deal, ...

These gene silencing proteins, referred to as Polycomb complexes, play critical roles in helping cells remember their own identity. While every type of cell in our body expresses a specific set of ...

High cost is a major challenge. The global cell and gene therapy market is projected to expand by $6.56b, reflecting an ...

(Nasdaq: VYGR), a biotechnology company dedicated to advancing neurogenetic medicines, today announced that it has selected a lead development candidate, VY1706, for its tau silencing gene therapy ...