高度近视在全球的患病率呈上升趋势，已成为严峻的健康挑战。高度近视性白内障作为高度近视最常见的并发症，发病年龄比年龄相关性白内障更早，严重影响患者工作期间的生活质量。由于晶状体核通常较硬，HMC 的手术干预难度较大，因此深入了解其发病机制对开发潜在治疗方法至关重要。

Ferroptosis, a form of iron-dependent programmed cell death ... Acetyl Coenzyme A; PUFAs, Polyunsaturated Fatty Acids; GSSG:Oxidized Glutathione; GSH, Glutathione; ACSL4, Acyl-CoA Synthetase ...

Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China CAS Key Laboratory for ...

Key Laboratory of Emergency and Trauma of Ministry of Education, Department of Radiotherapy, The First Affiliated Hospital of Hainan Medical University, Hainan Medical University, Haikou 571199, China ...

Erastin (ER), a ferroptosis inducer, kills tumor cells by generating and accumulating reactive oxygen species (ROS) within the cell, resulting in an iron-dependent oxidative damage-mediated ...