Recipient T cells recognize donor antigens via two distinct pathways: the direct pathway (intact donor MHC molecules displayed on donor antigen-presenting cells [APCs]) and the indirect pathway ...

Neuronal pathway finding is crucial for structured cellular organization and development of neural circuits within the nervous system. Neuronal pathway finding within the visual system has been ...

This month's cover highlights the article RudLOV is an optically synchronized cargo transport method revealing unexpected effects of dynasore by Akiko K. Satoh, Takunori Satoh and colleagues. The ...

1D). Thus, the disruption of either the Retromer or Commander-dependent endosomal retrieval pathways does not impair the viability or proliferation of these cells. Together, these global genetic ...

That change was linked to a rise in a modified form of cholesterol known as oxysterol. Lowering oxysterol, in both animal models and human stem cells, freed the trapped ABCA1 and restored the pathway ...

FORT WAYNE, Ind. (WANE) – A redevelopment project upwards of $50 million will bring a sports complex to life near downtown Fort Wayne. The long-abandoned North River property – 29 acres bound ...

This opioid pathway in the brain was specifically activated when the mice ate additional sugar, but not when they ate normal or fatty food. When the researchers blocked this pathway, the mice ...

Using the new data, along with existing datasets on gene activity in diabetic pancreas tissue, the researchers catalogued endothelial genes and signaling pathways that appear to be disrupted in ...