Topical antibiotics available for treating acne include clindamycin (1% gel, lotion, solution, or pledgets applied b.i.d.), erythromycin (2% gel, solution, or pledgets applied b.i.d.), and sodium ...
Clindamycin and erythromycin inhibit protein synthesis by irreversibly binding to the ribosomal 50S subunit of P. acnes (Physician's Desk Reference, 2001). Whereas erythromycin is bactericidal ...