Kingston wanted to reverse the process and use a DNA probe to pull down all proteins associated with a targeted DNA locus in vivo. He is quick to point out that this idea is not new ...
Reactions contained 1× Taqman universal master mix (Perkin-Elmer, Foster City, California), 300 nM forward primer, 300 nM reverse primer, 100 nM probe primer and 100–500 ng of template DNA in a ...
BHQnova ™ Probes are double-quenched hydrolysis probes with enhanced quenching and greater signal-to-noise ratio for long probes (>25 bases). Such probes consist of a 5' fluorophore dye ...
Teams led by LMU chemist Philip Tinnefeld have now published two studies showing how DNA origami and fluorescent probes can be used to release molecular cargo in a targeted manner. The system ...