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揭开细菌DNA超缠绕的秘密
来自杜伦大学、雅盖隆大学(波兰)和约翰英纳斯中心的研究人员在理解DNA旋转酶(DNA gyrase)方面取得了突破,这是一种重要的细菌酶和关键的抗生素靶点。 这种酶存在于细菌中,但在人类中不存在,它在DNA的超盘绕中起着至关重要的作用,这是细菌生存的 ...
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