We propose that this force-dependent regulation of nucleotide exchange is the basic mechanism of gating behaviour — a key regulation for the efficient hand-over-hand movement. The regulatory ...

Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as regulatory T-cells, and may serve as potential therapeutic targets to treat ...

The research, co-authored by MD/Ph.D. student Samantha "Sammy" Tse-Kang and Read Pukkila-Worley, MD, professor of medicine, uncovered a mechanism of effector-triggered immunity in animals ...

Despite this knowledge, the precise mechanism underlying the formation of these nascent membrane structures remains poorly understood. To gain insights into this process, researchers at the ...

A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy.