Patients in the clonidine group withdrew due either to adverse effects, with 3 patients developing symptomatic orthostatic hypotension, or lack of efficacy, with 2 patients experiencing seizures ...
This agent is chemically similar to the antihypertension medication clonidine. It acts through agonist effects on the alpha-2 adrenergic system at both the spinal and supraspinal levels to reduce ...
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