Gan’s lab investigates how other cell death mechanisms might be exploited in the fight against cancer. With the exception of mechanical injury — where a cell is physically torn apart — cell ...

inactivation of glutathione peroxidase 4 (GPx4), and iron-dependent propagation of LPO—has renewed interest in non-apoptotic ...

While autophagy is an essential cellular mechanism, this article will focus on other forms of cell death, such as apoptosis and controlled necrotic pathways. Necrosis, also known as Type III cell ...

DILI is broadly categorized into intrinsic and idiosyncratic types. Intrinsic hepatotoxins, such as APAP, cause ...

A groundbreaking study from IISc explores how bat-origin viruses manipulate cell death in humans, explaining the disparity in ...

Researchers are shining a light on cancer cells' energy centers—literally—to damage these power sources and trigger ...

More information: Ava Bachari et al, Evaluating the Mechanism of Cell Death in Melanoma Induced by the Cannabis Extract PHEC-66, Cells (2024). DOI: 10.3390/cells13030268 ...

Over time, however, this "garbage disposal" became overwhelmed by the protein aggregates, leading to cell death in the zebrafish retina. "The discovery of this mechanism was unexpected ...

Over time, however, this "garbage disposal" becomes overwhelmed by the protein aggregates, leading to cell death in the zebrafish retina. "The discovery of this mechanism was unexpected ...

elegans to analyze the mechanisms that drive apoptosis ... studies of worms have helped reveal how human cells govern cell death and pointed toward potential targets for treating disease.