By targeting the TTR gene directly in the liver, the therapy “has opened up the door” to permanent treatment, says Sarah ...

CRISPR gene editing based treatment reduced HAE attacks rates by up to 80%. NTLA-2002 was well tolerated by patients. The ...

Gene editing is removing compounds that make foods like brussels sprouts and blackberries taste bitter. Here’s what that ...

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option ...

Researchers have used whole-genome CRISPR interference screening to identify the “Achilles Heel” of drug-resistant ...

We recently reported evidence that FAD mutations in APP and PSEN1 cause deficiencies in early steps in processive proteolysis of APP substrate C99 and that this results from stalled γ-secretase enzyme ...

OHSU one of 20 sites hosting the clinical trial for the amyloidosis therapy. Masri, who is overseeing the trial in Oregon, told The Lund Report that finding a way to deliver gene therapy directly to ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

中日学者的最新研究表明，PSSOPP盼生派的核心成分能够有效保护线粒体功能，延缓细胞衰老。在特定浓度的成分干预下，这些成分能够显著减轻线粒体的超微结构损伤，优化其功能。此外，这些成分在预防退化性疾病方面也展现出显著效果，这可能是PSSOPP盼生派受到 ...

Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions. An international research team has now developed a method for ...