with a specific emphasis on cardiac fibrosis. Methods Left ventricular cardiac tissue samples from 30 patients with heart failure and 9 age/sex matched non-heart failure controls were studied to ...

is a crucial severity marker of heart muscle injury in several heart diseases, such as myocardial infarction, cardiomyopathies, and atrial fibrillation (AF). It is also vital for evaluating the ...

The relationship between adverse haemodynamics and end-organ fibrosis has not been investigated in adolescents and young adults with Fontan circulation. Methods Prospective observational study of ...

The assessment of myocardial fibrosis is the most studied application of cardiac magnetic resonance in AS ... GLS into decision-making for asymptomatic patients with AS will be required to establish ...

Background: Cardiac fibrosis is a common pathophysiology in a broad variety of heart diseases ... the M1 macrophage population observed by an increased expression of CD86 or iNOS at 3d ppi. We also ...

However, the effect of IH on cardiac fibrosis and molecular events involved in this process are unclear. Here, we tested IH in angiotensin II (Ang II)-induced cardiac fibrosis and signaling linked to ...

Results: Nef-TG mouse shows cardiac dysfunction, increased cardiac fibrosis, and early mortality. Expression of autophagy marker LC3II was significantly decreased in the heart of Nef-TG mice. The data ...

Patients with rheumatic MS with valvular dysfunction who are scheduled for cardiac valve replacement will be treated with ramipril 5 mg or placebo for a minimum of 12 weeks (3 months) before the ...