Stress granules (SGs) form in response to diverse environmental signals. Here, the signaling pathways that connect lysosomal stress to SG formation are characterized. A calcium-dependent pathway ...

Skeletal muscle tissue demonstrates global hypermethylation with aging. However, methylome changes across the time-course of ...

Under normal physiological conditions, FSH binds to FSHRs coupled to the Gαs protein, activating the cAMP/protein kinase A (PKA) and calcium signaling pathways. This pathway enhances glucose ...

For instance, β-arrestins mediate GPCR endocytosis by binding to clathrin and AP2 while participating in signal transduction by scaffolding the components of the MAPK pathway. Similarly ...

Newly discovered estrogen receptor-dependent signaling pathways demonstrate that ... actions of estrogen in four cell types. E2 induces MAPK phosphorylation and activation within 5 minutes in ...

A low blood calcium level is rare in people with cancer. The main cause of low calcium levels is having the parathyroid glands in your neck removed. This might be necessary for some types of cancer in ...

Calcium lactate is calcium paired with lactic acid. The body needs calcium to support bone, heart, muscle, and nerve health. Boosting calcium intake through supplements or food may help reduce cancer ...

Calcium is an important mineral that our bodies need to keep us healthy. Having cancer can affect the amount of calcium in the body. High blood calcium levels sometimes happen if your cancer is ...

Since the pivotal discovery of Calcium as the only ion able to produce muscle contraction by Lewis Victor Heilbrunn in 1947, several generations of scientists have sought to understand how this ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Retinoic acid (RA) signaling is a master ...

Researchers find that SARS-CoV-2 spike protein persists in the skull-meninges-brain axis, driving neuroinflammation, ...