【导读】目前仍亟需对基于CRISPR的技术进行精确控制。在这项研究中，团队设计了一套可通过聚焦超声（FUS）控制的可诱导CRISPR工具，它可以穿透深层并诱导局部热疗，以激活转基因。2024年12月1日，美国加州大学圣地亚哥分校Wang ...

A new CRISPR-Cas toolkit, dubbed "pAblo·pCasso," is set to transform the landscape of bacterial genome editing, offering unprecedented precision and flexibility in genetic engineering.

So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to their own genome to guide the Cas proteins, and the odd patterns of these bits of ...

as viruses try to inject their DNA into the bacterial genome and bacteria devise cunning methods (e.g. CRISPR) to defend ...

6, 2024 — The CRISPR ... that bacteria use to respond to viral ... Aug. 9, 2024 — A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and ...

Named Science Magazine’s 2015 Breakthrough of the Year, the CRISPR/Cas9 genome editing system has taken the biotechnology world by storm. CRISPR/Cas9—a technology derived from a naturally occurring ...

It has emerged as a powerful tool for genome engineering, with applications spanning from basic research to biotechnology and medicine. Bacteria and archaea possess adaptive immunity against foreign ...

This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...

Various types of endonucleases – enzymes that can cut DNA – were already known before CRISPR-Cas9. The discovery of restriction enzymes in the early 1970s heralded a new age in molecular biology.

CRISPR-based gene-editing tools are being developed to correct specific defective sections of the genome to cure inherited genetic diseases, with some applications already in clinical trials. However, ...