By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...

No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.

Both technologies had one major drawback: the nucleases used to cut DNA were inefficient. This changed with the development of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...

2025年1月24日，北京大学生命科学学院Jackson Champer课题组与合作者在《Nature Communications》期刊上发表了题为“Gene drive-based population suppression in the ...

"So we decided to use the CRISPR/Cas9 tool with which we achieved the genetic editing of two genes related to the recycling of nucleotides in their roots," continued the researcher. Thus ...

An extensive arsenal of biosensing tools has been developed based on the clustered regularly interspaced short palindromic repeat (CRISPR) platform, including those that detect specific DNA sequences ...