条件性基因敲除小鼠的设计利用了Cre/LoxP或Flipe/Frt原理。它们都是位点特异性重组酶系统。 Cre-LoxP 系统是一种基于位点特异性 ...

条件性基因敲除小鼠的设计利用了Cre/LoxP、Flipe/Frt、Dre-Rox等染色体（DNA）位点特异性重组酶系统，其中常用的是Cre-LoxP系统 ...

在当今的生命科学研究中，Cre小鼠和Flox小鼠作为重要的转基因小鼠模型，正在为基因功能的深入研究提供强有力的工具。这 ...

Conversely, we next generated FBXW7 fat-conditional knockout mice (FBXW7-FKO mice) by crossing FBXW7-LoxP mice with Adiponectin-Cre mice (Appendix Fig. S6A). We confirmed efficient and specific ...

Request permissions for this article. From the Saha Cardiovascular Research Center (C.W., A.D., H.S.L.), University of Kentucky, Lexington. Department of Physiology ...

Dave's been wielding mice in anger since the hoary ol' days of the Amiga 500, Deluxe Paint, and Dune 2. He even plugged one into his Commodore 64 once, but he got over that. He's had his paws on ...

Here’s how it works. The best cheap gaming mouse proves you don't have to break the bank to improve your gaming performance when playing the best PC games. You also won't have to sacrifice ...

ROCHESTER, N.Y. — Your favorite Disney stars are lacing up their skates and taking the ice at Blue Cross Arena for another ... Party” will take Mickey Mouse and his pals through Captain ...

Rob Cross openly admits that exhaustion may lead ... He added: "I can beat the best players in the world, but I can also lose to Mickey Mouse tomorrow morning. It's not a problem for me.