*仅供医学专业人士阅读参考把肿瘤微环境内因抗原慢性刺激转入耗竭状态的CD8+T细胞“叫醒”，让它们重新活化为效应CD8+T细胞，是PD-1/L1抑制剂为代表的现有免疫治疗起效的关键，但实话实说，激活处在耗竭状态的CD8+T细胞，在奇点糕眼里总觉得有点 ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

研究者表示，Asxl1能破坏其赋予T细胞优越的长期治疗潜力，而这或许是未来科学家们设计基于T细胞的免疫疗法的一种非常有希望的策略。 免疫疗法能利用患者自身的免疫系统来治疗疾病，其在一些癌症患者身上展现出了一定的希望，但对于大多数患者而言却并不奏效。近日，一篇发表在国际杂志Science上题为“Epigenetic regulators of clonal hematopoiesis control ...

2024年10月1日，温州医科大学附属第一医院陈钢团队在期刊《Gut Microbes》上发表了题为“Synergistic activity of Enterococcus Faecium-induced ferroptosis via ...

In a study of identical twins, a team led by PD Dr. Lisa Ann Gerdes (Institute of Clinical Neuroimmunology at LMU University ...

Discover research by Hongbo Chi, PhD, that uncovers the interplay between organelles, nutrient-dependent signaling pathways ...

A study involving identical twins suggests alterations in immune cells called CD8 T-cells may be early drivers of ...

之前已有研究探索了多肽-MHC融合蛋白与其他分子在红细胞中调控免疫反应以治疗癌症的作用，而仅含有MHC-I分子的红细胞在免疫激活方面的有效性仍有待研究。 2023年9月，高晓飞团队在 Cell Research ...

"NIH selects Emergex’s T cell vaccine for trials under Project NextGen" was originally created and published by Clinical ...

CAR-T cell products’ quality control standards incorporate characterization, uniformity, and purity testing to ensure and ...

Immatics, a biotech company working on promising cell-based immunotherapies for solid cancers, has a promising TCR-engineered ...