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Objectives In this study, we employ a multiomic approach to identify major cell types and subsets, and their transcriptomic profiles within the infrapatellar fat pad (IFP), and to determine ...
(19) The selectivity test was performed by analyzing samples containing either the ligand or the internal standard (IS) using LC-MS/MS to ensure that there were no interfering peaks. The ligand showed ...
As an emerging biomarker, ESRP1 has a decisive impact on the formation and development of solid tumors by regulating the alternative splicing of CD44 and the epithelial-mesenchymal transition (EMT) ...
为解决急性肾损伤(AKI)机制不明及治疗策略缺乏的问题,南方医科大学研究人员探究 CD44 在 AKI 中的作用。结果发现 CD44 可加重 AKI,抑制它或成治疗新策略。推荐科研读者阅读,以了解 AKI 新机制与潜在疗法。 在当今社会,急性肾损伤(AKI)就像一个隐藏在 ...
Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection. During sepsis, the coagulation cascade is ...
The deshielded CTNCs readily interact with the CD44 receptor on the tumor cells via the HA ligand of CTNCs. Once the CTNCs are selectively internalized by CRC cells, the intracellular esterase of ...
such as fibronectin 1-cluster of differentiation 44 (FN1-CD44) and C-X-C motif chemokine ligand 12-C-X-C motif chemokine receptor 4 (CXCL12-CXCR4). Furthermore, three upregulated genes (spectrin ...