METHODS: We studied endocrine function in 32 patients (age, 6 to 65 years) 2 to 13 years after they had received cranial radiotherapy for brain tumors. The doses of radiation to the hypothalamic ...

The hypothalamus secretes corticotropin releasing ... Typical doses of dexamethasone used in the brain tumor patient are pharmacologic (i.e., supraphysiologic) in nature and have the potential ...

There exists a dire need to improve treatments for malignant brain tumors. Current strategies, including surgery, radiation, and chemotherapies, can have serious side effects and are generally not ...

Researchers from the School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry.