A study reveals why monkeys resist HBV infection, showing that specific amino acid differences in their NTCP receptor prevent ...

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases that spreads among individuals through blood ...

Hepatitis B virus (HBV) has a narrow host range, mainly infecting hominoids. A new study reveals the structural differences in the liver cell receptor (NTCP) between humans and monkeys, explaining why ...

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids. According ...

The table below is a review of notable updates that occurred in November 2024 for investigational products in development (not an inclusive list). Click on the status to view our full coverage.

Vitamin D deficiency has been correlated with increased rates of infection. Since the early 19th century, both environmental (i.e., sunlight) and dietary sources (cod liver) of vitamin D have been ...

This latest update comes after Advanz secured a suspension of the European Commission’s original revocation in September 2024 ...

Nutrient GPCRs were expressed throughout the mouse GI tract from stomach to colon, with the exception of the sweet taste receptor T1R2 that was detected only in the small intestine (figure 1). The ...

Ocaliva is a potent and selective agonist of the farnesoid X receptor (FXR), which is expressed at high levels in the liver and intestine and thought to be a key regulator of bile acid ...

The FDA has approved 43 novel drugs so far this year (January-November), compared to 52 during the same period last year. As we step ...

Expert Rev Cardiovasc Ther. 2008;6(3):391-409. Phosphatidic acid phosphatase/phosphohydrolase (PAP) is an enzyme that catalyzes the conversion of phosphatidic acid to ...