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赛沃替尼有效克服 MET 扩增介导的 EGFR-TKI 耐药,联合治疗 PFS 长达 15 ...
目前多项研究显示间质表皮转化因子(MET)扩增是导致表皮生长因子受体(EGFR)酪氨酸激酶抑制剂(TKI)继发性耐药的重要机制[1,2]。既往耐药患者缺乏有效治疗,随着 MET 抑制剂的出现,越来越多证据显示 MET-TKI 联合 EGFR-TKI可有效克服耐药。本期「In China For Global - MET 新例量」分享 1 例 EGFR ...
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