BRAF V600E mutations are common in different tumor types (more frequently in melanomas, colon and thyroid carcinomas). BRAF Alterations in Brain Tumors: Different Diagnostic Relevance of BRAF ...

Novartis' two-drug regimen of Tafinlar and Mekinist has been approved by the FDA as the first therapy for solid tumours that have a BRAF V600E mutation – regardless of where they occur in the body.

BRAF V600E突变患者相比其他患者预后更差 ... 没有任何位点显示MSI，即MSS。 MMR蛋白的IHC检测，需同时检测4个常见MMR蛋白（MLH1、MSH2、MSH6和PMS2）的表达。其中≥1 种表达缺失，判定为错配修复基因缺陷（dMMR ...

Erratum: Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor–Mutant Non–Small-Cell Lung Cancer ...

We conducted a prospective experience on samples classified as TNBC, analyzed by IHC and by FISH, in order to evaluate discordant cases between IHC and FISH and to enable patients misclassified as ...

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International Holding Co's (IHC) outlook on investments in India's Adani Group remains unchanged, the Abu Dhabi conglomerate said following the U.S. indictment of billionaire Gautam Adani.