BODIPY-Cholesterol在碳24处带有荧光BODIPY基团，这一设计不仅保留了BODIPY荧光团的高亮度、高稳定性和可调谐的光谱特性，还赋予了探针与细胞膜、特别是富含胆固醇的细胞膜区域（如细胞膜微域）的高亲和力。 作为胆固醇类似物，BODIPY-cholesterol具有良好的亲脂性和 ...

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (NCNST), Beijing 100190, P. R. China ...

Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China ...

This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...

马来酰亚胺聚乙二醇叠氮(MAL-PEG-N3)是MAL PEG的硫醇反应性“点击化学”PEG交联剂之一。马来酰亚胺与pH 6.5-7.5的游离巯基/巯基 ...

The study highlights adhesion G-protein-coupled receptor A3 (ADGRA3) as a potential target for activating adaptive thermogenesis in both white and brown adipose tissue. This finding offers valuable ...

而目前的J型聚集体仅限于有限的染料系统，例如花菁（Cy）、硼二吡咯甲烯（BODIPY）和苝酰亚胺（PDI），往往面临着合成困难、稳定性差、弱的活性 ...

1Department of Diagnostic Radiology, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, Singapore. 2Nanomedicine Translational Research ...

Bacterial infections and antibiotic resistance are global health problems, and current treatments for bacterial infections still rely on the use of antibiotics. Phototherapy based on the use of a ...

胰腺癌是一种恶性程度极高的肿瘤，其5年生存率仅为10%，主要原因在于80%的患者表现为不可切除或存在转移性疾病。虽然手术 ...