A 64-year-old man presented to the haematology clinic with an isolated mild lymphocytosis, which was found to be due to B cell prolymphocytic leukaemia (B-PLL). Other than previous Barrett’s ...

Genome studies of diffuse large B-cell lymphoma (DLBCL) have revealed a large number of somatic mutations and structural alterations. However, the clinical significance of these alterations is ...

T-cell large granular lymphocytic leukemia (T-LGLL) and T-cell prolymphocytic leukemia are rare hematologic malignancies. T-LGLL is caused by pro-inflammatory states, such as rheumatoid arthritis and ...

Chronic lymphocytic leukemia (CLL) is a type of cancer that starts in white blood cells (called lymphocytes) in the bone marrow. CLL mainly affects older adults and accounts for about one-third of all ...

CCAR-066 (CBM.CD20 CAR-T) is under development for the treatment of chemotherapy resistant or refractory CD20+ leukemia and lymphoma including b-cell non-Hodgkin lymphoma, follicular lymphoma, mantle ...

The purpose of this study is to evaluate the safety and effectiveness of venetoclax plus ibrutinib for participants with T-cell Prolymphocytic Leukemia (T-PLL) and follows a 2-stage design as follows: ...

prolymphocytic leukemia, small lymphocytic lymphoma, recurrent glioblastoma, follicular lymphoma, mantle cell lymphoma, chronic lymphocytic leukemia (CLL), relapsed/refractory multiple myeloma (MM), ...