Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

Diabetes drug development gets an advance in study that shows Inceptor binds excess insulin within the beta cell and directs it towards degradation.

AMPK is a central regulator of metabolism and autophagy. Here we show how lysosomal damage activates AMPK. This occurs via a hitherto unrecognized signal transduction system whereby cytoplasmic ...

Damaged or superfluous proteins and other components inside a cell are broken down in a process called autophagy. Aging research has established that autophagy pathways become less active with age ...

This was accompanied by an impairment of mitochondrial function with reduced expression of carnitine palmitoyltransferase I and an induction of acyl-coenzyme A oxidase-1 (ACOX1), oxidative stress and ...

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Scientists speculate that Semaglutide, as a GLP-1 receptor analog, represents a peptide with broad research potential beyond ...

Research indicates that cannabis use causes cellular damage that increases the risk of highly cancerous tumors by disrupting ...