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Structural research on RSV F protein has identified seven different antigenic epitopes, termed Site Ø, I, II, III, IV, V, and a quaternary dependent (QD) site, with only I, II, and IV being ...

There are 18 recognized HA subtypes (H1–H18). 1,2,5 Antigenic drift and antigenic shift, which lead to variations in HA subtypes, drive the seasonal patterns of human influenza outbreaks.

Prior to vaccine availability, RSV was a significant cause of illness and hospitalization in older adults in the U.S., particularly those 60 and older. Before respiratory syncytial virus (RSV) ...

Among the viruses circulating most are COVID-19, flu and RSV. So far this season, the CDC estimates, there have been at least 24 million flu illnesses, 310,000 hospitalizations and 13,000 deaths ...

Respiratory syncytial virus (RSV) is the most important cause of infantile bronchiolitis and pneumonia. It is ubiquitous, with most children acquiring their primary infection within the first year ...

The respiratory syncytial virus (RSV) vaccine triggered strong immune responses among people aged 60 years and older during its first two seasons for use, according to the final findings of a phase 3 ...

Functions of each viral protein are listed in Table 1. Antigenic drift is the process whereby mutations accumulate in viral surface glycoproteins (predominantly hemagglutinin), resulting in ...

2). Classical vaccines such as diphtheria and tetanus, for instance, target toxin antigens that have not had antigenic drift during the past century. Other antigens with little or no antigenic ...