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These included genetic models such as androgen receptor knockout mice and chronic androgen exposure in females using dihydrotestosterone (DHT) implants. Subsequently, they analyzed DNA from ...

The understanding of the biology of CRPC and the evidence that CRPC still remains driven by androgen receptor signaling led to the discovery of new therapeutic targets. In the last few years ...

1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...

Anthony Joshua. Dr. Sandhu notes that androgen receptor signal directly contributes to taxane resistance, thus cabazitaxel efficacy can be improved by simultaneous blocking the androgen receptor in ...

and it also blocks androgen receptors in the skin. Estrogen stimulates angiotensin synthesis and enhances aldosterone-mediated water and sodium retention, making it responsible for such unpleasant ...

Treating Prostate Cancer With Novel Platinum Complex Via Targeting Androgen Receptor Signaling Dec. 16, 2024 — Prostate cancer, especially in advanced stages such as castration-resistant ...

1Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California. 2Department of Radiation Oncology, University of California, San Francisco, San ...

Jan. 15, 2025 — Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins ...

TOR signalling and integrin signalling. Sevenless, the Drosophila homologue of ROS1 (dROS1) is a receptor tyrosine kinase essential for the differentiation of photoreceptor cells and activated by ...

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