Innovative Research Combines Ayurvedic Medicine and Chemically Designed Peptides to Combat Amyloid Aggregation in ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

Lab-grown mini-brains help scientists explore how concussions reactivate latent viral infections, triggering molecular ...

Hereditary transthyretin (hATTR) amyloidosis is a rare progressive disease that is passed from parent to child. It is caused by a mutant form of the transthyretin (TTR) protein that can damage vital ...

“As we understand, Alzheimer’s is a multifactorial disease, and though amyloid plaques and tau protein play an important part ...

The rate of frailty among patients with multiple sclerosis (MS) ranges from 17% to 66% among ambulatory patients, and frailty among MS patients is linked to a host of complications. Read about the ...

Our research includes work conducted by our Global Oncology program in sub-Saharan Africa and China as well as scores of other studies that span the globe from North and South America to Europe and ...

Elucidation of part of the Mechanism by which Lecanemab Slows the Progression of Alzheimer's Disease ...

The pathophysiology of conduction disease in CA remains elusive, being most likely the result of the interplay between a variety of mechanisms: autonomic dysfunction, especially in patients with AL or ...

Pathophysiology and Biomarkers: The pathophysiology of AD involves the progressive neurodegeneration from initial amyloid pathology to overt dementia over 15-20 years. Biomarkers, particularly ...

This article is part of the Research Topic The Role of Glial Cells in the Pathophysiology and Treatment of Alzheimer's Disease. View all 6 articles This was done as previously described (Wijesinghe et ...