This excess LDL-influx leads to an eventual accumulation of neutral lipid droplets around LD-R amastigotes, thereby increasing their unresponsiveness towards Amphotericin-B, a second-line amphiphilic ...

Background: Cryptococcal meningitis (CM) is a significant global health issue, particularly affecting individuals with HIV. Amphotericin B (AmB) serves as the cornerstone treatment for CM; however, ...

Intravenous amphotericin B should be reserved for those with severe disease. Oral triazole antifungals have had a great impact on the management of coccidioidomycosis. Both fluconazole and ...

We used peripheral blood mononuclear cells (PBMCs) cultured in the presence of autologous serum to test the impact of complement activation and inhibition on cytokine release, testing the effects of ...

and rigors associated with anesthesia or drug therapy (typically chemotherapy or amphotericin B). Interventions were made for all patients receiving meperidine for pain management. Almost all ...

and the structure, shape and size of zygospores (sexual stage) including suspensory cells. Fungal identification guides provide sufficient identification keys and subsequently information on the ...

For Cresemba, this comprises a milestone payment for sales in Canada, by AVIR Pharma Inc, as well as the first sales milestone payment for the Middle East and North Africa (MENA) region, by Hikma ...

This structure allows them to encapsulate both hydrophilic drugs (in the aqueous core ... 3,5 Liposomes are also used in antifungal therapies, such as Ambisome®, to deliver amphotericin B with reduced ...

Molson Coors Beverage Co. Cl A 6.28% $12.44B Molson Coors Beverage Co. Cl B 3.11% $12.44B ...

The company has one clinical-stage candidate in SF001, an analogue of the well-established antifungal amphotericin B that Elion describes ... with a “novel chemical structure and binding mode.” ...

Berkshire Hathaway Inc., through its subsidiaries, engages in the insurance, freight rail transportation, and utility businesses worldwide. The company provides property, casualty, life, accident ...