Experts clear up the confusion on lactic acid, the burning sensation you feel in your legs during hard efforts, how to ...

Low-intensity Zone 2 workouts may sound simple, but they can improve metabolic health, help regulate blood sugar, and enhance ...

Metabolic alterations in cancer cells are numerous and include aerobic glycolysis, reduced oxidative phosphorylation and the increased generation of biosynthetic intermediates needed for cell ...

1Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea. 2Laboratory of Immune Regulation in Department of Biomedical Sciences, Seoul National University College of ...

In summary, there is a clear discrepancy in therapeutically targeting the LDHA-mediated aerobic glycolysis in activated immune cells and other tissues. While inhibiting LDHA activity primarily ...

Her current work focuses on modeling and investigating healthy and diseased retinas at the cellular and molecular levels. She pioneered a modeling approach to investigate the steps of aerobic ...

Despite an increase in glycolysis, however, here we show that non-transformed mouse fibroblasts also increase oxidative phosphorylation (OXPHOS) by nearly two-fold and mitochondrial coupling ...

By monitoring single-cell dynamics in each of these contexts, we identified PI3K/Akt regulation of glycolysis as a multifaceted modulator of single-cell metabolic dynamics that is required to maintain ...