The purine structure consists of a pyrimidine ring (positions 1 to 6) fused to an imidazole ring (positions 7 to 9). Adenine and guanine, the two most common purines in DNA and RNA, share this core ...

Adenine was first discovered in 1885 by the German physiologist Albrecht Kossel. He isolated adenine from the pancreas of oxen and named it "adenine" derived from the Greek word "aden," meaning gland.

Chemical structural formulas of purine and pyrimidine... Chemical structural formulas of purine and pyrimidine nitrogenous bases: adenine (A, Ade), guanine (G, Gua) , thymine (T, Thy), uracil (U), ...

Elion was assigned a subgroup called purines. (Two of the four bases in DNA are purines -- adenine and guanine.) Hitchings reasoned that since bacteria, tumors, and certain parasites need large ...

the purine bases adenine and guanine, which are building blocks of DNA. They soon discovered, from observing the role of purines in nucleic acid metabolism, that bacterial cells require certain ...

The results showed that 9-BTG inhibited the utilization of preformed purines for DNA synthesis under conditions in which RNA synthesis and the incorporation of glycine into proteins and nucleic acids ...

General uric acid lowering treatment sometimes causes the onset of gout, but the specific cause is not clear. Our group has found that adenine nucleoside triphosphate (ATP) plays an important role in ...