In mice, inhibiting protein S-palmitoylation Counteracted accumulation of harmful proteins in neurons and delayed onset and progression of cognitive decline.
Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, ...
Nascent HDL obtains free cholesterol from peripheral tissues. A circulating enzyme called lecithin:cholesterol acyltransferase promotes the uptake of free cholesterol by HDL by a reaction called ...