LNZ100 is a single-use, once-daily eye drop containing aceclidine, a small molecule acetylcholine receptor agonist that causes miosis. The NDA is supported by data from the CLARITY phase 3 program ...

The disease most commonly affects muscles that control eye and eyelid movement ... the message is called acetylcholine. When acetylcholine binds to a nerve receptor, your muscle knows to contract.

In myasthenia gravis, the receptors for acetylcholine at the muscle surface are destroyed ... The symptoms range from difficulty in eye motion which results in double vision or droopy eyelids, to ...

These cells have synapses that are packed with receptors for acetylcholine, which is the primary neurotransmitter released by motor neurons. When acetylcholine binds to the receptors on a skeletal ...