production systems combined with facile adaptability for an extended repertoire of AAV serotypes are required to keep pace with the rapidly increasing clinical demand. For scalable high-titer ...

With their increasing adoption, precise tools are vital for quantifying AAV capsid titers and detecting anti-AAV antibodies to ensure the safety, efficacy and proper dosing of therapies. This ...

providing higher workflow flexibility and a more detailed assessment of AAV viral titer and capsid integrity. Utilizing Droplet Digital ™ PCR (ddPCR), Bio-Rad Laboratories developed a new ...

Immunological investigations showed rheumatoid factor levels of 100 IU/mL, an antinuclear antibody titer of 1:80, and myeloperoxidase antibodies of 200 RU/mL ... The patient’s antibiotics were stopped ...

Below is our list of the 29 largest contracts in MLB history by average annual value (AAV). Please note that if a player was already under contract and signed an extension, only the new money counts.

causing HDFN The woman's anti-D antibody titer remains detectable DAT = direct agglutination test; FMH = fetal-maternal hemorrhage; HDFN = hemolytic disease of the fetus and newborn; IAGT ...

Objective Adeno-associated virus (AAV) is a defective mono-stranded DNA virus, endemic in human population (35%–80%). Recurrent clonal AAV2 insertions are ...

To address this limitation, Nishiyama et al. expanded CRISPR/Cas9-mediated HDR to post-mitotic neurons in various ages, cell types, and brain regions. This method is based on a high titer AAV-mediated ...