AAV-mediated neurogenesis phenocopies the neurogenesis we observed from transgenic ... Interestingly, the types of neurons generated by the MG are dictated by the transcription factors expressed and ...

AAV vectors are widely used in the scientific ... organoid at day 36 for neural stem cell marker NESTIN (red) and neuron TUJ1 (green) markers with nuclei visualized by a DAPI counterstain.

Finally, AAV transduction was performed by transducing ... can trigger dopaminergic neuron degeneration and the disruption of other neurons’ dendrites in a concentration-dependent manner ...

We injected adeno-associated virus (AAV) into the VTA for Cre-dependent expression of Channelrhodopsin-2 (ChR2) fused to mCherry that labels distal axons (Figure 1A). To test whether the labeled VTA ...

imed3.med.osaka-u.ac.jp Objectives Inappropriate activation of neutrophils plays a pathological role in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). The aim of this study ...

好书推荐！《动物行为实验指南》电子版pdf，网盘发货《动物行为实验指南》共674页，涵盖了常见的实验动物，如小鼠、大鼠和斑马鱼，详细描述了每一种行为测试的实验设计、测试设备、实验流程、评估指标、预期结果、常见问题及解决方法、数据分析、模型应用与局限性 ...

Synapses play a pivotal role in forming neural circuits, with critical implications for brain functions such as learning, memory, and emotions. Several advances in synaptic research have demonstrated ...

基于时间间隔的多巴胺信号传递是强化学习的基础，它倾向于支持那些能驱动具有积极结果的行为的神经活动模式。在纹状体中，多巴胺激活五种多巴胺受体（D1R-D5R），这些受体在纹状体神经元中的表达存在差异。然而，特定多巴胺受体在强化过程中的作用尚不清楚。20 ...