Cachexia is a serious yet under-recognized consequence of many chronic diseases, including heart disease, kidney disease, chronic obstructive pulmonary disease and, most notably, cancer.

No writing assistance was utilized in the production of this manuscript. RANKL expression is stimulated in osteoblasts and osteocytes by cytokines and hormones, and plays an important role in ...

Researchers discovered a drug that safely and effectively helped cancer patients when they suffered from cachexia (ku-KEK-see-uh), a common condition related to cancer that involves weight loss ...

The experimental drug ponsegromab is a monoclonal antibody that treats the growth factor that leads to the growth of cancer ...

Cachexia involves loss of appetite and weight, muscle-wasting, fatigue, and weakness. It affects more than 50 percent of ...

Pfizer’s cancer cachexia candidate has provided patients with clinically meaningful weight gain in a Phase II trial, with the company sharing aims to start a pivotal programme in 2025.