IT has been demonstrated that, besides heparin and histamine, mast cells contain serotonin (5-hydroxytryptamine, 5-HT) 1–3. However, serotonin-containing mast cells, having been found ...

Blueprint Medicines Corporation (Nasdaq: BPMC) today announced data presentations reflecting its ongoing efforts to innovate ...

A doctor has issued a warning about a lifelong medical condition that can cause 'unexplained' symptoms and is frequently ...

Histamine makes lots of changes in your body. It adjusts your blood vessels and tissues so more immune cells can rush to the area. It makes a bunch of mucus. It tells the muscles in your airways, ...

Systemic mastocytosis is a disease where too many abnormal mast cells (a type of white blood cell) build up in your skin and other organs. You might get a variety of symptoms, including itchy skin ...

Allergic inflammation plays a big role in allergy reactions and contributes to the itching and chewing commonly seen with ...

1 Pathogenesis of CSU: The Role of Mast Cells Understanding the role of mast cells is key to grasping the underlying mechanisms of CSU. Mast cells, particularly the MCTC subtype found in the skin ...

At the recent AAAAI/WAO meeting, Blueprint Medicines Corp. presented the in vitro and in vivo characterization of BLU-808, a selective inhibitor of wild-type KIT, a transmembrane receptor tyrosine ...

(NASDAQ:CLDX) announced today positive preclinical data from CDX-622, a novel bispecific antibody that targets two non-redundant, complementary pathways implicated in inflammation and fibrosis—thymic ...

THB-335 is an oral inhibitor of mast/stem cell growth factor receptor Kit (KIT), which regulates the activation and migration of mast cells, making it a relevant therapeutic target for inflammatory ...

Live webcasts of the presentations will be available on the News & Events – Events page of Jasper's Investor Relations website. An archived replay of each presentation will be available on Jasper's ...