Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

The mitotic spindle is the microtubule-based bipolar structure that segregates the chromosomes in mitosis. The poles of the mitotic spindle are made up of centrosomes and the chromosomes are lined ...

The subsequent breakdown of the nuclear envelope terminates prophase and initiates prometaphase, during which the chromosomes become attached to and positioned on the mitotic spindle as it forms.