Despite being mainly composed of terminally differentiated myocytes that cannot re-enter the cell cycle, the heart is not a postmitotic organ and maintains some capacity to form new parenchymal ...
BACKGROUND: Cardiomyocytes in the adult human heart show a regenerative capacity, with an annual renewal rate of ≈0.5%. Whether this regenerative capacity of human cardiomyocytes is employed in heart ...
[5] an effect which may in part be due to direct stimulation of cardiac myocytes or central and humoral activation. The effect of caffeine is more pronounced in subjects who do not drink coffee ...
allowing for rapid and localized regulation of channel activity in restricted subcellular microdomains within cardiac myocytes. These findings suggest that an ideal antiarrhythmic agent may be one ...
The field of cardio-immunology has gained significant attention as heart disease has become the leading cause of death globally over the past two decades. Despite advancements in managing hemodynamic ...
These include effects on arterial smooth muscle cells that cause intense peripheral vasoconstriction and stimulation of cardiac myocytes and fibroblasts. The latter promotes phenotypic changes in ...