JAUNDICE is a common presentation of Wilson's disease and may precede the neurologic features by many years. 1,2 Infective hepatitis is often invoked as an explanation of the initial episode ...

Osteoporosis is a common complication of chronic liver disease. Although bone demineralization has been noted in Wilson's disease—which involves pathologic copper accumulation—the exact ...

Adapted from Schilsky ML, Tavil AS. Wilson disease. In: Schiff's Diseases of the Liver. Philadelphia: Lippincott Williams and Wilkins; 2006:1023–1040. Most practitioners prefer start with trientine.