Universal rRNA depletion can put the power of RNA-seq at the disposal of researchers studying any organism, from dangerous pathogens to vital plant crops. The RNA sequencing (RNA-seq) revolution ...

Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. RNA is more subject to degradation than DNA, whether chemical, ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Analyzing RNA profiles can aid in early diagnosis, prognosis, and monitoring treatment response. RNA-based diagnostic tools, such as RT-PCR and RNA sequencing, are widely used for detecting and ...

In this interview, we gain a behind the scenes look at Morgan’s recently published paper in BioTechniques, ‘RNA Extraction and RNA-Sequencing Method for Transcriptomic Analysis of Mycobacterium ...

目前，癌症的诊断主要依赖实验室检查和影像学技术的联合应用。然而，这种方式不仅给患者带来了沉重的经济负担，而且无法完全替代病理检查在诊断中的核心地位。于是，寻找可靠的癌症生物标志物，实现早期筛查和诊断，成为临床科学家们不懈探索的方向。在这个过程中，细胞外囊泡尤其是外泌体，因其含有 DNA、RNA ...

This is thanks to advances in bulk and single-cell RNA-sequencing (RNA-seq) technologies that can capture every RNA molecule expressed in a cell: its transcriptome. The computational methods ...

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to ... By delivering mRNA encoding the correct protein sequence into cells, it is possible to restore the ...