However, recent studies have indicated new roles for centrosomes in cytokinesis and cell-cycle progression. Is it possible that a common 'thread' connects all three sets of findings? Careful ...

Proper structure and function of duplicated mitotic centrosomes are required for fidelity in chromosome segregation and preservation of diploidy. We have shown that in breast tumors centrosome ...

The resulting cells, locked together like Siamese twins, would have twice as many chromosomes and centrosomes, making them unfit and prone to malignancy. Many cancer cells, for example ...