In a study published in Cell Reports Physical Science on Nov. 25, a research team reported the development of an innovative ...

RNAi is activated by introducing double-stranded RNA homologous to the target gene transcript. The exogenous RNA is digested in to small interfering RNAs (siRNA), which bind a nuclease complex to form ...

To get more sustained knockdown effects, researchers have the option of producing siRNA from either a plasmid or viral vector. Many groups have made siRNA adenovirus, adenovirus-associate virus ...

In a study published in Cell Reports Physical Science on Nov. 25, a research team led by Prof. CAI Lintao from the Shenzhen Institutes of Advanced ...

vector therapies for rare genetic diseases, 3 small interfering RNA (siRNA) therapies, 4 antisense oligonucleotide (ASO) therapies, 3 adenovirus (Ad) vector-based vaccines, and 2 messenger RNA ...