Although I am confident of the 1.5% engraftment in patient 1 and of the mesenchymal type of the cells, I am doubtful that the presence of 1.5–2% normal osteoblasts could lead to a fourfold ...

There is a variation in the symptoms and severity of OI from person to person. Osteogenesis imperfecta can result in more severe complications. Signs and symptoms range from mild to severe.[ ...

Osteogenesis imperfecta (OI) is an inherited (genetic ... Most babies with OI have a defect of one of two genes which help in forming collagen. Collagen is a main part of connective tissue ...

Osteogenesis imperfecta ... with type 2 being the most severe form of the disease. People with types 4, 5, and 6 tend to have more moderate symptoms. And those with type 1, which is the most ...