In this new study, the researchers found a genetic variant that results in differences in tubulin protein production between ...

Microtubules are the largest type of filament, with a diameter of about 25 nanometers (nm), and they are composed of a protein called tubulin. Actin filaments are the smallest type, with a ...

The taxanes exert their cytotoxic effect by binding tubulin, stabilizing the microtubule and inhibiting its disassembly, ultimately leading to cell death by apoptosis. Although there is no maximum ...

Researchers from Hebei Normal University and affiliated organizations presented the discovery and preclinical characterization of a novel B lymphoma Mo-MLV insertion region 1 (Bmi-1) expression ...

Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...

A phase 1/2 study evaluating the safety and efficacy of autologous TAC T cells in subjects with claudin 18.2+ advanced solid tumors. This is an ASCO Meeting Abstract from the 2025 ASCO ...