Self-reactive T cells slipping past thymic defenses to seed peripheral lymphoid organs require a different strategy to tame their autoimmune potential 8. Reduced Treg function contributes to ...

Regulatory T cells (Tregs) help keep the immune system from kicking in at inappropriate times and causing autoimmune ...

Francis S. Kim, MD, has made significant contributions to biomedical research and clinical care for adult and pediatric ...

AstraZeneca has selected a candidate to progress in the type 1 diabetes (T1D) Treg cell therapy programme, as per an 18 ...

A Japanese research team has found a new way to curb cancer cells in the immune system and are now pushing for a clinical ...

TIL-Tregs specifically increase GLUT3 expression for glucose uptake in tumors. - GLUT3 fuels protein O-GlcNAcylation, ...

This is the first significant research milestone achieved under its 2023 collaboration agreement with AstraZeneca to develop, manufacture and commercialize autologous, engineered Treg cell therapies ...

Researchers at the Medical University of South Carolina and the University of Florida recently collaborated on a novel, ...

The firm is also studying PTG-007 in patients with early-stage type 1 diabetes, but is looking for a partner for the pivotal trial.

LPX-TI641 is an oral novel Treg-expanding T cell/transmembrane, immunoglobulin, and mucin (Tim)receptor agonist therapy in development for the ...