BACKGROUND: Transcatheter closure of patent foramen ovale (PFO) after cryptogenic stroke has long been a contentious issue. Herein, we pool aggregate data examining safety and efficacy of ...

med. Lars Kellert in issue 31–32/2017 In their article on juvenile stroke, the authors also comment on indication for interventional closure of patent foramen ovale (PFO) (1). On the basis of a ...

This well-done negative trial definitively demonstrates no benefit to PFO closure in patients with cryptogenic stroke and argues strongly that these patients should either be treated with medical ...

Much remains to learn about this anatomical finding, seen in about one-third of adults, and how it may affect stroke risk.

Patients with cryptogenic stroke treated with routine transcatheter patent foramen ovale closure have increased 4-year stroke risk.