The complement system is an important part of the humoral immune defence in mammals that is formed by about 35 soluble and cell-surface proteins. Together these proteins enable the host to ...

The complement system consists of a cascade of linked proteins that are activated in response to infection or tissue damage.

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Now, over 100 years after the complement system was first described, researchers at Mass General Brigham have discovered that a protein known as granzyme K (GZMK) drives tissue damage and ...

The Complement group, headed by Prof. Seppo Meri, has for long had an interest in sorting out how and why the complement system contributes to disease pathogenesis, how the system is controlled and ...