Other essential cellular pseudoknots have been described in telomerase RNA and transfer messenger RNA. Future research into pseudoknots will focus on structure–function relationships and ...

The analysis of the involvement of crisis in tumorigenesis has been aided by genetically defined cancer-prone mice that lack telomerase activity. These mouse models have provided insights into the ...

Continually proliferating cells maintain adequate telomeres through the action of the reverse transcriptase telomerase. Telomeres are important to human health because dysregulation of either telomere ...

I do this two times. The numbers you get can be used later to determine the amount of human TERT made during this translation. Immunopurify the human telomerase with HA beads washed with 1X human ...

Subsequent work by Blackburn and Greider identified that enzyme, which is now known as telomerase, and showed that it was composed of both a protein and a molecule of RNA that serves a template for ...

It works by regulating the production of human telomerase reverse transcriptase, a protein that affects tumour formation. RNA editing has some advantages over DNA editing, especially on safety and ...