Scientists have uncovered the hidden danger of how high iron levels from red meat may increase the risk of colorectal cancer.

A new study reveals the connection between dietary iron and cancer progression, paving the way for targeted therapies in ...

Telomerase is an enzyme that can compensate for this shortening by maintaining telomeres at a stable length, helping to protect chromosomes against degradation and fusion. Mutations that ...

Our research in this area aims to understand how telomere-associated proteins protect and maintain telomeres. Key questions include how subunits of the telomerase enzyme contribute to activity, how ...

The three were honored for “for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.” According to the Royal Swedish Academy, this year’s Nobel Prize in Physiology or ...

By restoring youthful levels of a key component of the telomerase enzyme, they have successfully reversed aging-related symptoms in laboratory models. If these findings translate to humans ...

The more common mechanism which is active in 85 90% of human cancer cells is to switch on TERT, the protein component of telomerase (a ribonucleoprotein enzyme that synthesizes telomeres ...

Many scientists are not sure what to think about potential extra-telomeric functions for telomerase. But it is hard to understand why the enzyme activity would go up so dramatically, and in our case, ...

Dr. Tollefsbol's laboratory is also interested in the epigenetic regulation of the gene that produces telomerase (hTERT) and in unraveling the mysteries of how this gene relates to cancer and aging.